Principal Scientist - Computational Toxicology

OUR COMPANY At Boehringer Ingelheim we develop breakthrough therapies and innovative healthcare solutions in areas of unmet medical need for both humans and animals. As a family owned company, we focus on long-term performance. We believe that, if we have talented and ambitious people who are passionate about innovation, there is no limit to what we can achieve; after all, we started with just 28 people. Now, we are powered by 50,000 employees globally who nurture a diverse, collaborative and inclusive culture. THE POSITION Apply your passion. Turn data into insights. Improve patients´ lives. Join a world class team of toxicologist and contribute to informed decision making in the course of preclinical drug development. We are looking for biological scientist who is passionate in using digital innovative methodologies to generate new insights in toxicological data for the benefit of our patients. A core responsibility is to use data science to reveal possible modes of action that enable the translation of in vivo safety findings from preclinical species into patient populations. Tasks & responsibilities As a company representative, you take over responsibility to enable toxicity data sharing initiatives (IMI eTRANSAFE and Biocelerate) and explore consortia and in-house toxicological data. In your new role you integrate your systems biology knowledge with emerging Computational Chemistry methods e.g. from areas such as artificial intelligence and chemoinformatics on toxicological data.  You discover possible mode of actions for toxicity findings and enable de-risking strategy. You enable the development and implementation of new modelling and simulation strategies for drug safety with a focus on systemic toxicology. In addition, you will support the project teams in identifying and reducing safety concerns through the development and application of computational approaches. This role includes working in a collaborative team environment as part of the comprehensive safety assessment of BI´s new chemical entity portfolio. Through your expertise, you work cross-functionally with computational experts from related disciplines such as Medicinal Chemistry, Computational Biology and DMPK. Requirements Master´s degree or PhD in toxicology, bio-chemistry, veterinary medicine, computer science, or related discipline as well as demonstrated experience in toxicology along with several years of experience in the pharmaceutical industry or other relevant organization Sound Knowledge of SEND Expertise in database generation and scripting in R or other widely used programming languages like Python is desired Demonstrated experience in extracting, compiling and analyzing complex data sets for building QSAR/machine learning models is desired. It is preferred that the candidate also has additional technical skills in the field of computational chemistry or computational biology Teamplayer with strong communicational skills  WHY BOEHRINGER INGELHEIM? This is where you can grow, collaborate, innovate and improve lives.  We offer challenging work in a respectful and friendly global working environment surrounded by a world of innovation driven mindsets and practices. In addition, learning and development for all employees is key, because your growth is our growth. We also offer a competitive salary, generous amount of vacation time, and numerous benefits towards your wellness & financial
  • Standort: Biberach

Boehringer Ingelheim

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